Review

Systematic review of methods for evaluating healthcare research economic impact

Bahareh Yazdizadeh¹ , Reza Majdzadeh² and Hojat Salmasian³

¹  Department of Biostatistics and Epidemiology, School of Public Health and Knowledge Utilization Research Center, Tehran University of Medical Sciences, Tehran, Iran

²  Knowledge Utilization Research Center and Department of Biostatistics and Epidemiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

³  Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran

author email corresponding author email

Health Research Policy and Systems 2010, 8:6doi:10.1186/1478-4505-8-6

Published:	2 March 2010

Abstract

Background

The economic benefits of healthcare research require study so that appropriate resources can be allocated to this research, particularly in developing countries. As a first step, we performed a systematic review to identify the methods used to assess the economic impact of healthcare research, and the outcomes.

Method

An electronic search was conducted in relevant databases using a combination of specific keywords. In addition, 21 relevant Web sites were identified.

Results

The initial search yielded 8,416 articles. After studying titles, abstracts, and full texts, 18 articles were included in the analysis. Eleven other reports were found on Web sites. We found that the outcomes assessed as healthcare research payback included direct cost-savings, cost reductions in healthcare delivery systems, benefits from commercial advancement, and outcomes associated with improved health status. Two methods were used to study healthcare research payback: macro-economic studies, which examine the relationship between research studies and economic outcome at the aggregated level, and case studies, which examine specific research projects to assess economic impact.

Conclusions

Our study shows that different methods and outcomes can be used to assess the economic impacts of healthcare research. There is no unique methodological approach for the economic evaluation of such research. In our systematic search we found no research that had evaluated the economic return of research in low and middle income countries. We therefore recommend a consensus on practical guidelines at international level on the basis of more comprehensive methodologies (such as Canadian Academic of Health Science and payback frameworks) in order to build capacity, arrange for necessary informative infrastructures and promote necessary skills for economic evaluation studies.